Anti-ICK Antibody
Boster Bio Anti-ICK Antibody catalog # A06270-2. Tested in ELISA, IF, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Serine/threonine-protein kinase ICK;2.7.11.1
Gene Name
ICK
UniProt
Q9UPZ9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human ICK
Clonality
Polyclonal
Tissue Specificity
Expressed in heart, brain, placenta, pancreas, thymus, prostate, testis, ovary, small intestine and colon, with highest levels in placenta and testis. Not detected in spleen. Also expressed in many cancer cell lines.
Applications
IHC, IF, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
Required for ciliogenesis (PubMed:24797473) . Phosphorylates KIF3A (By similarity) . Involved in the control of ciliary length (PubMed:24853502) . Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity) . May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity) . Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity (By similarity) .
Molecular Weight
71427 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Serine/threonine-protein kinase ICK
Subcellular Location
Nucleus
Protein Name
Serine/threonine-protein kinase ICK
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