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Anti-GPR37L1 Antibody

Boster Bio Anti-GPR37L1 Antibody catalog # A11679-1. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

G-protein coupled receptor 37-like 1; Endothelin B receptor-like protein 2; ETBR-LP-2; GPR37L1; ETBRLP2;

Gene Name

GPR37L1

UniProt

O60883

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human ETBR2. AA range:1-50

Clonality

Polyclonal

Tissue Specificity

Expressed in primary cortical astrocytes (at protein level) (PubMed:23690594) . Expressed in the central nervous system (PubMed:9539149) .

Applications

WB, IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

G-protein coupled receptor (PubMed:27072655) . Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade (PubMed:23690594) . However, other studies have shown that prosaposin does not increase activity (PubMed:27072655, PubMed:28688853) . It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G (s) subunit alpha (PubMed:27072655) . Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway (By similarity) . Regulates baseline blood pressure in females and protects against cardiovascular stress in males (By similarity) . Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity (By similarity) .

Molecular Weight

52771 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

G-protein coupled receptor 37-like 1

Subcellular Location

Cell membrane

Protein Name

G-protein coupled receptor 37-like 1

Frequently Asked Questions