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Anti-GPR31 Antibody

Boster Bio Anti-GPR31 Antibody catalog # A14413. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

12- (S) -hydroxy-5,8,10,14-eicosatetraenoic acid receptor;12- (S) -HETE receptor;12-HETER; G-protein coupled receptor 31; GPR31;

Gene Name

GPR31

UniProt

O00270

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human GPR31. AA range:181-230

Clonality

Polyclonal

Applications

WB, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

High-affinity receptor for 12- (S) -hydroxy-5,8,10,14- eicosatetraenoic acid (12-S-HETE) . 12- (S) -HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B.

Molecular Weight

35075 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

12- (S) -hydroxy-5,8,10,14-eicosatetraenoic acid receptor

Subcellular Location

Cell membrane

Protein Name

12- (S) -hydroxy-5,8,10,14-eicosatetraenoic acid receptor

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