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Anti-GDF-9 Antibody

Boster Bio Anti-GDF-9 Antibody catalog # A01466-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Growth/differentiation factor 9; GDF-9; GDF9;

Gene Name

GDF9

UniProt

O60383

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human GDF-9. AA range:273-322

Clonality

Polyclonal

Tissue Specificity

Expressed in ovarian granulosa cells. Present in oocytes of primary follicles (at protein level) .

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.

Molecular Weight

51444 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Growth/differentiation factor 9

Subcellular Location

Secreted .

Protein Name

Growth/differentiation factor 9

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