What is the catalog number for Anti-E2F-6 Antibody?

The catalog number for Anti-E2F-6 Antibody is A05062-1.

What sizes are available for Anti-E2F-6 Antibody?

Anti-E2F-6 Antibody is available in the following size(s): 100 µL.

Is Anti-E2F-6 Antibody in stock?

Anti-E2F-6 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-E2F-6 Antibody?

The safety data sheet for Anti-E2F-6 Antibody is available here: https://www.bosterbio.com/msds?sku=A05062-1.

Anti-E2F-6 Antibody

Boster Bio Anti-E2F-6 Antibody catalog # A05062-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Transcription factor E2F6; E2F-6; E2F6;

Gene Name

E2F6

UniProt

O75461

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human E2F6. AA range:141-190

Clonality

Polyclonal

Tissue Specificity

Expressed in all tissues examined. Highest levels in placenta, skeletal muscle, heart, ovary, kidney, small intestine and spleen.

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase.

Molecular Weight

31844 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Transcription factor E2F6

Subcellular Location

Nucleus.

Protein Name

Transcription factor E2F6

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