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Anti-Dorfin RNF19A Antibody

Boster Bio Anti-Dorfin RNF19A Antibody catalog # A07593. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

E3 ubiquitin-protein ligase RNF19A;2.3.2.31

Gene Name

RNF19A

UniProt

Q9NV58

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human RNF19A. AA range:51-100

Clonality

Polyclonal

Tissue Specificity

Widely expressed, with highest levels in heart. Ubiquitously expressed in the central nervous system.

Applications

WB, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as SNCAIP or CASR. Specifically ubiquitinates pathogenic SOD1 variants, which leads to their proteasomal degradation and to neuronal protection.

Molecular Weight

90696 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

E3 ubiquitin-protein ligase RNF19A

Subcellular Location

Membrane ; Multi-pass membrane protein . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

Protein Name

E3 ubiquitin-protein ligase RNF19A

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