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Anti-DOCK 2 Antibody

Boster Bio Anti-DOCK 2 Antibody catalog # A03836-2. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Dedicator of cytokinesis protein 2; DOCK2; KIAA0209;

Gene Name

DOCK2

UniProt

Q92608

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human DOCK 2.

Clonality

Polyclonal

Tissue Specificity

Specifically expressed in hematopoietic cells. Highly expressed in peripheral blood leukocytes, and expressed at intermediate level in thymus and spleen. Expressed at very low level in the small intestine and colon.

Applications

IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.

Molecular Weight

211948 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A03836-2

Product MSDS

https://www.bosterbio.com/msds?sku=A03836-2

Fragment

IgG

Other Gene Names

Dedicator of cytokinesis protein 2

Subcellular Location

Endomembrane system

Protein Name

Dedicator of cytokinesis protein 2

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