Anti-Cytochrome P450 4V2 CYP4V2 Antibody
Boster Bio Anti-Cytochrome P450 4V2 CYP4V2 Antibody catalog # A05648-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Cytochrome P450 4V2;1.14.14.-; Docosahexaenoic acid omega-hydroxylase CYP4V2 ;1.14.14.79
Gene Name
CYP4V2
UniProt
Q6ZWL3
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of human CYP4V2.
Clonality
Polyclonal
Tissue Specificity
Broadly expressed. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, retina, retinal pigment epithelium (RPE) and lymphocytes.
Applications
WB, IHC, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
Omega-hydroxylase that oxidizes medium-chain saturated fatty acids and polyunsaturated omega-3 fatty acids, and which plays a role in fatty acid and steroid metabolism in the eye (PubMed:19661213, PubMed:22772592) . Catalyzes the omega- hydroxylation of medium-chain saturated fatty acids such as laurate, myristate and palmitate in an NADPH-dependent pathway. The substrate specificity is higher for myristate > laurate > palmitate (C14>C16>C12) (PubMed:19661213) . Acts as a polyunsaturated omega-3 fatty acids hydroxylase by mediating oxidation of docosahexaenoate (DHA) to 22-hydroxydocosahexaenoate (PubMed:22772592) . Also produces some 21-hydroxydocosahexaenoate. Also converts eicosapentaenoate (EPA) to 20- hydroxyeicosapentaenoate (20-OH-EPA) (PubMed:22772592) .
Molecular Weight
60724 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Cytochrome P450 4V2
Subcellular Location
Endoplasmic reticulum membrane
Protein Name
Cytochrome P450 4V2
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