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Anti-Cyclin H CCNH Antibody

Boster Bio Anti-Cyclin H CCNH Antibody catalog # A03013-3. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Cyclin-H; MO15-associated protein; p34; p37; CCNH;

Gene Name

CCNH

UniProt

P51946

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Cyclin H. AA range:274-323

Clonality

Polyclonal

Applications

WB, IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

Molecular Weight

37643 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A03013-3

Product MSDS

https://www.bosterbio.com/msds?sku=A03013-3

Fragment

IgG

Other Gene Names

Cyclin-H

Subcellular Location

Nucleus.

Protein Name

Cyclin-H

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