What is the catalog number for Anti-CARD 14 Antibody?

The catalog number for Anti-CARD 14 Antibody is A04906-2.

What sizes are available for Anti-CARD 14 Antibody?

Anti-CARD 14 Antibody is available in the following size(s): 100 µL.

Is Anti-CARD 14 Antibody in stock?

Anti-CARD 14 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-CARD 14 Antibody?

The safety data sheet for Anti-CARD 14 Antibody is available here: https://www.bosterbio.com/msds?sku=A04906-2.

Anti-CARD 14 Antibody

Boster Bio Anti-CARD 14 Antibody catalog # A04906-2. Tested in ELISA, IF, IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Caspase recruitment domain-containing protein 14; CARD-containing MAGUK protein 2; Carma 2; CARD14; CARMA2;

Gene Name

CARD14

UniProt

Q9BXL6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human CAR14. AA range:291-340

Clonality

Polyclonal

Tissue Specificity

Isoform 1 is detected in placenta and epidermal keratinocytes (PubMed:22521418) . Isoform 2 is detected in leukocytes and fetal brain (PubMed:22521418) .

Applications

IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Acts as a scaffolding protein that can activate the inflammatory transcription factor NF-kappa-B and p38/JNK MAP kinase signaling pathways. Forms a signaling complex with BCL10 and MALT1, and activates MALT1 proteolytic activity and inflammatory gene expression. MALT1 is indispensable for CARD14- induced activation of NF-kappa-B and p38/JNK MAP kinases (PubMed:11278692, PubMed:21302310, PubMed:27113748, PubMed:27071417) . May play a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis.