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Anti-BCL-6 corepressor BCoR Antibody

Boster Bio Anti-BCL-6 corepressor BCoR Antibody catalog # A01440. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

BCL-6 corepressor; BCoR; BCOR; KIAA1575;

Gene Name

BCOR

UniProt

Q6W2J9

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human BCOR. AA range:1231-1280

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed.

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence- specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2) .

Molecular Weight

192189 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01440

Product MSDS

https://www.bosterbio.com/msds?sku=A01440

Fragment

IgG

Other Gene Names

BCL-6 corepressor

Subcellular Location

Nucleus

Protein Name

BCL-6 corepressor

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