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Anti-Bak BAK1 Antibody

Boster Bio Anti-Bak BAK1 Antibody catalog # A01163-1. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7; BAK1; BAK, BCL2L7, CDN1;

Gene Name

BAK1

UniProt

Q16611

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human Bak. AA range:1-50

Clonality

Polyclonal

Tissue Specificity

Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.

Applications

ELISA, IF, IHC, WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases.

Molecular Weight

23409 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Bcl-2 homologous antagonist/killer

Subcellular Location

Mitochondrion outer membrane

Protein Name

Bcl-2 homologous antagonist/killer

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