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Anti-ARRDC3 Antibody

Boster Bio Anti-ARRDC3 Antibody catalog # A07177-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Arrestin domain-containing protein 3; TBP-2-like inducible membrane protein

Gene Name

ARRDC3

UniProt

Q96B67

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human ARRDC3. AA range:365-414

Clonality

Polyclonal

Tissue Specificity

Highly expressed in skeletal muscle, placenta, kidney, lung, liver, blood, adrenal gland, lymph node, mammary gland, thyroid, and trachea (PubMed:16269462, PubMed:21982743) . Very low levels in colon, thymus, spleen, small intestine, bladder and bone marrow (PubMed:16269462) . Strong expression in differentiated adipocytes compared to preadipocytes (PubMed:16269462) . Detected in omental fat and subcutaneous fat tissue (PubMed:21982743) .

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Adapter protein that plays a role in regulating cell- surface expression of adrenergic receptors and probably also other G protein-coupled receptors (PubMed:20559325, PubMed:21982743, PubMed:23208550) . Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation (PubMed:20559325, PubMed:23208550) . May recruit NEDD4 to ADRB2 (PubMed:20559325) . Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes (PubMed:23208550) .

Molecular Weight

46395 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Arrestin domain-containing protein 3

Subcellular Location

Cytoplasm

Protein Name

Arrestin domain-containing protein 3

Frequently Asked Questions

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