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Anti-Arrdc1 Antibody

Boster Bio Anti-Arrdc1 Antibody catalog # A16232. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Arrestin domain-containing protein 1 ; Alpha-arrestin 1

Gene Name

ARRDC1

UniProt

Q8N5I2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human ARRD1. AA range:167-216

Clonality

Polyclonal

Applications

WB, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:23886940, PubMed:27462458) . Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458) . More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles (PubMed:22315426) . By participating to the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway (PubMed:23886940) .

Molecular Weight

45981 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A16232

Product MSDS

https://www.bosterbio.com/msds?sku=A16232

Fragment

IgG

Other Gene Names

Arrestin domain-containing protein 1

Subcellular Location

Cell membrane

Protein Name

Arrestin domain-containing protein 1

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