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Anti-ARHGAP22 Antibody

Boster Bio Anti-ARHGAP22 Antibody catalog # A10197. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Rho GTPase-activating protein 22; Rho-type GTPase-activating protein 22; ARHGAP22; RHOGAP2;

Gene Name

ARHGAP22

UniProt

Q7Z5H3

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human RHG22. AA range:565-614

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter (By similarity) . .

Molecular Weight

76779 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Rho GTPase-activating protein 22

Subcellular Location

Cytoplasm . Nucleus . Mainly cytoplasmic. Some fraction is nuclear (By similarity) . .

Protein Name

Rho GTPase-activating protein 22

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