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Anti-AF-10 MLLT10 Antibody

Boster Bio Anti-AF-10 MLLT10 Antibody catalog # A04471-1. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Protein AF-10 ; ALL1-fused gene from chromosome 10 protein; MLLT10

Gene Name

MLLT10

UniProt

P55197

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human AF10. AA range:211-260

Clonality

Polyclonal

Tissue Specificity

Expressed abundantly in testis.

Applications

WB, IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation (PubMed:26439302) .

Molecular Weight

113320 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Protein AF-10

Subcellular Location

Nucleus

Protein Name

Protein AF-10

Curated Selection

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