Anti-ACE1 Antibody
Boster Bio Anti-ACE1 Antibody catalog # A00251-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Angiotensin-converting enzyme; ACE;3.2.1.-;3.4.15.1; Dipeptidyl carboxypeptidase I; Kininase II; CD143; Angiotensin-converting enzyme, soluble form; ACE; DCP, DCP1;
Gene Name
ACE
UniProt
P12821
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human ACE1. AA range:891-940
Clonality
Polyclonal
Tissue Specificity
Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis.
Applications
WB, IHC, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.
Molecular Weight
149715 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Angiotensin-converting enzyme
Subcellular Location
Angiotensin-converting enzyme, soluble form: Secreted.
Protein Name
Angiotensin-converting enzyme
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