Anti-Phospho-EpoR (Y426) Antibody
Boster Bio Anti-Phospho-EpoR (Y426) Antibody catalog # A00427Y426. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Erythropoietin receptor; EPO-R; EPOR;
Gene Name
EPOR
UniProt
P19235
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human EpoR (phospho Tyr426)
Clonality
Polyclonal
Tissue Specificity
Erythroid cells and erythroid progenitor cells. Isoform EPOR-F is the most abundant form in EPO-dependent erythroleukemia cells and in late-stage erythroid progenitors. Isoform EPOR-S and isoform EPOR-T are the predominant forms in bone marrow. Isoform EPOR-T is the most abundant from in early- stage erythroid progenitor cells.
Applications
WB, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.
Molecular Weight
55065 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Erythropoietin receptor
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Protein Name
Erythropoietin receptor
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