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Anti-Phospho-HIRA (T555) Antibody

Boster Bio Anti-Phospho-HIRA (T555) Antibody catalog # A03101T555. Tested in ELISA, IF, IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Protein HIRA; TUP1-like enhancer of split protein 1; HIRA; DGCR1, HIR, TUPLE1;

Gene Name

HIRA

UniProt

P54198

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human HIRA around the phosphorylation site of Thr555. AA range:521-570

Clonality

Polyclonal

Tissue Specificity

Expressed at high levels in kidney, pancreas and skeletal muscle and at lower levels in brain, heart, liver, lung, and placenta.

Applications

IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.

Molecular Weight

111835 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Protein HIRA

Subcellular Location

Nucleus. Nucleus, PML body. Primarily, though not exclusively, localized to the nucleus. Localizes to PML bodies immediately prior to onset of senescence.

Protein Name

Protein HIRA

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