Anti-Phospho-IP3R-I (S1598) ITPR1 Antibody
Boster Bio Anti-Phospho-IP3R-I (S1598) ITPR1 Antibody catalog # A01465S1598. Tested in ELISA, IF, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Inositol 1,4,5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; InsP3R1; Type 1 inositol 1,4,5-trisphosphate receptor; Type 1 InsP3 receptor; ITPR1; INSP3R1;
Gene Name
ITPR1
UniProt
Q14643
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Inositol 1,4,5-trisphosphate R1 around the phosphorylation site of Ser1598/1588. AA range:1566-1615
Clonality
Polyclonal
Tissue Specificity
Widely expressed.
Applications
IHC, IF, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate (PubMed:27108797) . Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity) . Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity) .
Molecular Weight
313929 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Inositol 1,4,5-trisphosphate receptor type 1
Subcellular Location
Endoplasmic reticulum membrane
Protein Name
Inositol 1,4,5-trisphosphate receptor type 1
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