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Anti-Phospho-DAPK2 (S318) Antibody

Boster Bio Anti-Phospho-DAPK2 (S318) Antibody catalog # A02241S318. Tested in ELISA, IF, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Death-associated protein kinase 2; DAP kinase 2;2.7.11.1

Gene Name

DAPK2

UniProt

Q9UIK4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human DAPK2 around the phosphorylation site of Ser318. AA range:284-333

Clonality

Polyclonal

Tissue Specificity

Expressed in neutrophils and eosinophils (PubMed:24163421) . Isoform 2 is expressed in embryonic stem cells (at protein level) . Isoform 1 is ubiquitously expressed in all tissue types examined with high levels in heart, lung and skeletal muscle.

Applications

IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation (PubMed:17347302) . Regulates granulocytic motility by controlling cell spreading and polarization (PubMed:24163421) .

Molecular Weight

42898 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A02241S318

Product MSDS

https://www.bosterbio.com/msds?sku=A02241S318

Fragment

IgG

Other Gene Names

Death-associated protein kinase 2

Subcellular Location

Cytoplasm. Cytoplasmic vesicle, autophagosome lumen.

Protein Name

Death-associated protein kinase 2

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