What is the catalog number for Anti-Phospho-HtrA2 (S142) Antibody?

The catalog number for Anti-Phospho-HtrA2 (S142) Antibody is A01941S142.

What sizes are available for Anti-Phospho-HtrA2 (S142) Antibody?

Anti-Phospho-HtrA2 (S142) Antibody is available in the following size(s): 100 µL.

Is Anti-Phospho-HtrA2 (S142) Antibody in stock?

Anti-Phospho-HtrA2 (S142) Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Phospho-HtrA2 (S142) Antibody?

The safety data sheet for Anti-Phospho-HtrA2 (S142) Antibody is available here: https://www.bosterbio.com/msds?sku=A01941S142.

Anti-Phospho-HtrA2 (S142) Antibody

Boster Bio Anti-Phospho-HtrA2 (S142) Antibody catalog # A01941S142. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Serine protease HTRA2, mitochondrial;3.4.21.108; High temperature requirement protein A2; HtrA2; Omi stress-regulated endoprotease; Serine protease 25; Serine proteinase OMI; HTRA2; OMI, PRSS25;

Gene Name

HTRA2

UniProt

O43464

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human HtrA2 (phospho Ser142)

Clonality

Polyclonal

Tissue Specificity

Isoform 1 is ubiquitous. Isoform 2 is expressed predominantly in the kidney, colon and thyroid.

Applications

IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.

Molecular Weight

48841 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Serine protease HTRA2, mitochondrial

Subcellular Location

Mitochondrion intermembrane space. Mitochondrion membrane ; Single-pass membrane protein . Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment, and stimulation of mitochondria with caspase-8 truncated BID/tBID.