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Anti-Phospho-Dok-2 (Y345) Antibody

Boster Bio Anti-Phospho-Dok-2 (Y345) Antibody catalog # A07956Y345. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Docking protein 2; Downstream of tyrosine kinase 2; p56 (dok-2) ; DOK2;

Gene Name

DOK2

UniProt

O60496

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human Dok-2 (phospho Tyr345)

Clonality

Polyclonal

Tissue Specificity

Highly expressed in peripheral blood leukocytes, lymph nodes and spleen. Lower expression in thymus, bone marrow and fetal liver.

Applications

IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation (By similarity) . .

Molecular Weight

45379 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Docking protein 2

Protein Name

Docking protein 2

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