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Anti-Phospho-SRF (T159) Antibody

Boster Bio Anti-Phospho-SRF (T159) Antibody catalog # A00557T159. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Serum response factor; SRF; SRF;

Gene Name

SRF

UniProt

P11831

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human SRF around the phosphorylation site of Thr159. AA range:126-175

Clonality

Polyclonal

Applications

IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS) . Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics. Required for cardiac differentiation and maturation.

Molecular Weight

51593 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A00557T159

Product MSDS

https://www.bosterbio.com/msds?sku=A00557T159

Fragment

IgG

Other Gene Names

Serum response factor

Subcellular Location

Nucleus

Protein Name

Serum response factor

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