Anti-Phospho-SRF (T159) Antibody
Boster Bio Anti-Phospho-SRF (T159) Antibody catalog # A00557T159. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Serum response factor; SRF; SRF;
Gene Name
SRF
UniProt
P11831
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human SRF around the phosphorylation site of Thr159. AA range:126-175
Clonality
Polyclonal
Applications
IHC, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS) . Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics. Required for cardiac differentiation and maturation.
Molecular Weight
51593 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Serum response factor
Subcellular Location
Nucleus
Protein Name
Serum response factor
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