Anti-Phospho-APC1 (S355) ANAPC1 Antibody

Boster Bio Anti-Phospho-APC1 (S355) ANAPC1 Antibody catalog # A03471S355. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Anaphase-promoting complex subunit 1; APC1; Cyclosome subunit 1; Mitotic checkpoint regulator; Testis-specific gene 24 protein; ANAPC1; TSG24;

Gene Name

ANAPC1

UniProt

Q9H1A4

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human APC1 around the phosphorylation site of Ser355. AA range:321-370

Clonality

Polyclonal

Applications

IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.