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Anti-Phospho-FADD (S191) Antibody

Boster Bio Anti-Phospho-FADD (S191) Antibody catalog # A00237S191. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse.

Product Specifications

Synonyms

FAS-associated death domain protein; FAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity; Protein FADD; FADD; MORT1; GIG3;

Gene Name

FADD

UniProt

Q13158

Host

Rabbit

Reactivity

Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from mouse FADD around the phosphorylation site of Ser191. AA range:157-206

Clonality

Polyclonal

Tissue Specificity

Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes.

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

Molecular Weight

23279 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A00237S191

Product MSDS

https://www.bosterbio.com/msds?sku=A00237S191

Fragment

IgG

Other Gene Names

FAS-associated death domain protein

Protein Name

FAS-associated death domain protein

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