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Anti-Phospho-p16 (S326) CDKN2A Antibody

Boster Bio Anti-Phospho-p16 (S326) CDKN2A Antibody catalog # A00016S326. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Cyclin-dependent kinase inhibitor 2A

Gene Name

CDKN2A

UniProt

P42771

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human p16-INK4a around the phosphorylation site of Ser152. AA range:107-156

Clonality

Polyclonal

Tissue Specificity

Widely expressed but not detected in brain or skeletal muscle. Isoform 3 is pancreas-specific.

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.

Molecular Weight

16533 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Cyclin-dependent kinase inhibitor 2A

Subcellular Location

Cytoplasm

Protein Name

Cyclin-dependent kinase inhibitor 2A

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