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Anti-Phospho-MDMX (S367) MDM4 Antibody

Boster Bio Anti-Phospho-MDMX (S367) MDM4 Antibody catalog # A01889S367. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Protein Mdm4; Double minute 4 protein; Mdm2-like p53-binding protein; Protein Mdmx; p53-binding protein Mdm4; MDM4; MDMX;

Gene Name

MDM4

UniProt

O15151

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human MDM4 around the phosphorylation site of Ser367. AA range:336-385

Clonality

Polyclonal

Tissue Specificity

Expressed in all tissues tested with high levels in thymus.

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.

Molecular Weight

54864 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01889S367

Product MSDS

https://www.bosterbio.com/msds?sku=A01889S367

Fragment

IgG

Other Gene Names

Protein Mdm4

Subcellular Location

Nucleus.

Protein Name

Protein Mdm4

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