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Anti-Phospho-Ephrin-B1/2/3 (Y324) EFNB1 Antibody

Boster Bio Anti-Phospho-Ephrin-B1/2/3 (Y324) EFNB1 Antibody catalog # A02767Y324. Tested in ELISA, IHC-P, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Ephrin-B1; EFL-3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; LERK-2; Ephrin-B1 C-terminal fragment

Gene Name

EFNB1

UniProt

P98172

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Ephrin B1/B2/B3 around the phosphorylation site of Tyr324. AA range:290-339

Clonality

Polyclonal

Tissue Specificity

Widely expressed (PubMed:8070404, PubMed:7973638) . Detected in both neuronal and non-neuronal tissues (PubMed:8070404, PubMed:7973638) . Seems to have particularly strong expression in retina, sciatic nerve, heart and spinal cord (PubMed:7973638) .

Applications

ELISA, IHC-P, WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development (PubMed:8070404, PubMed:7973638) . Binding to Eph receptors residing on adjacent cells leads to contact- dependent bidirectional signaling into neighboring cells (PubMed:8070404, PubMed:7973638) . Shows high affinity for the receptor tyrosine kinase EPHB1/ELK (PubMed:8070404, PubMed:7973638) . Can also bind EPHB2 and EPHB3 (PubMed:8070404) . Binds to, and induces collapse of, commissural axons/growth cones in vitro (By similarity) . May play a role in constraining the orientation of longitudinally projecting axons (By similarity) .

Molecular Weight

38007 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A02767Y324

Product MSDS

https://www.bosterbio.com/msds?sku=A02767Y324

Fragment

IgG

Other Gene Names

Ephrin-B1

Subcellular Location

Cell membrane

Protein Name

Ephrin-B1

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