Anti-Phospho-WWOX (Y33) Antibody
Boster Bio Anti-Phospho-WWOX (Y33) Antibody catalog # A01223Y33. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
WW domain-containing oxidoreductase;1.1.1.-; Fragile site FRA16D oxidoreductase; Short chain dehydrogenase/reductase family 41C member 1; WWOX; FOR, SDR41C1, WOX1;
Gene Name
WWOX
UniProt
Q9NZC7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human WWOX around the phosphorylation site of Tyr33. AA range:18-67
Clonality
Polyclonal
Tissue Specificity
Widely expressed. Strongly expressed in testis, prostate, and ovary. Overexpressed in cancer cell lines. Isoform 5 and isoform 6 may only be expressed in tumor cell lines.
Applications
WB, IHC, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity) . May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF) -mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.
Molecular Weight
46677 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
WW domain-containing oxidoreductase
Subcellular Location
Cytoplasm
Protein Name
WW domain-containing oxidoreductase
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