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Anti-Phospho-Trk C (Y516) NTRK3 Antibody

Boster Bio Anti-Phospho-Trk C (Y516) NTRK3 Antibody catalog # A02502Y516. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

NT-3 growth factor receptor;2.7.10.1; GP145-TrkC; Trk-C; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase; NTRK3; TRKC;

Gene Name

NTRK3

UniProt

Q16288

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Trk C around the phosphorylation site of Tyr516. AA range:482-531

Clonality

Polyclonal

Tissue Specificity

Widely expressed but mainly in nervous tissue. Isoform 2 is expressed at higher levels in adult brain than in fetal brain.

Applications

WB, IHC, ELISA, Flow Cytometry

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.

Molecular Weight

94428 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

NT-3 growth factor receptor

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

NT-3 growth factor receptor

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