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Anti-Phospho-IGF-IIR (S2409) IGF2R Antibody

Boster Bio Anti-Phospho-IGF-IIR (S2409) IGF2R Antibody catalog # A00951S2409. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse.

Product Specifications

Synonyms

Cation-independent mannose-6-phosphate receptor; CI Man-6-P receptor; CI-MPR; M6PR;300 kDa mannose 6-phosphate receptor; MPR 300; Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; IGF-II receptor; M6P/IGF2 receptor; M6P/IGF2R; CD222; IGF2R; MPRI;

Gene Name

IGF2R

UniProt

P11717

Host

Rabbit

Reactivity

Human, Mouse, Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human IGF2R around the phosphorylation site of Ser2409. AA range:2381-2430

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.

Molecular Weight

274375 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Cation-independent mannose-6-phosphate receptor

Subcellular Location

Lysosome membrane

Protein Name

Cation-independent mannose-6-phosphate receptor

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