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Anti-Phospho-Topo I alpha (S1106) TOP2A Antibody

Boster Bio Anti-Phospho-Topo I alpha (S1106) TOP2A Antibody catalog # A00953S1106-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

DNA topoisomerase 2-alpha;5.99.1.3; DNA topoisomerase II, alpha isozyme; TOP2A; TOP2;

Gene Name

TOP2A

UniProt

P11388

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human TOP2A around the phosphorylation site of Ser1106. AA range:1081-1130

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity) .

Molecular Weight

174385 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

DNA topoisomerase 2-alpha

Subcellular Location

Cytoplasm

Protein Name

DNA topoisomerase 2-alpha

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