Anti-Phospho-PTP1B (S50) PTPN1 Antibody

Boster Bio Anti-Phospho-PTP1B (S50) PTPN1 Antibody catalog # A00613S50. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat.

Product Specifications

Synonyms

Tyrosine-protein phosphatase non-receptor type 1;3.1.3.48; Protein-tyrosine phosphatase 1B; PTP-1B; PTPN1; PTP1B;

Gene Name

PTPN1

UniProt

P18031

Host

Rabbit

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human PTP1B around the phosphorylation site of Ser50. AA range:16-65

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.

Molecular Weight

49967 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Tyrosine-protein phosphatase non-receptor type 1

Subcellular Location

Endoplasmic reticulum membrane

Protein Name

Tyrosine-protein phosphatase non-receptor type 1

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