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Anti-Phospho-PLC gamma (Y771) PLCG1 Antibody

Boster Bio Anti-Phospho-PLC gamma (Y771) PLCG1 Antibody catalog # A00677Y771. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat.

Product Specifications

Synonyms

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1;3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1; PLCG1; PLC1;

Gene Name

PLCG1

UniProt

P19174

Host

Rabbit

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human PLCG1 around the phosphorylation site of Tyr771. AA range:736-785

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) . Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand- mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.

Molecular Weight

148532 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

Subcellular Location

Cell projection, lamellipodium. Cell projection, ruffle. Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment.

Protein Name

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

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