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Anti-Phospho-Synaptotagmin 1/2 (T202/199) SYT1 Antibody

Selected Variant

A02314T202

Size: 100 µL

Boster Bio Anti-Phospho-Synaptotagmin 1/2 (T202/199) SYT1 Antibody catalog # A02314T202. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Synaptotagmin-1; Synaptotagmin I; SytI; p65; SYT1; SVP65, SYT;

Gene Name

SYT1

UniProt

P21579

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Synaptotagmin around the phosphorylation site of Thr202. AA range:176-225

Clonality

Polyclonal

Tissue Specificity

Expressed in melanocytes (PubMed:23999003) .

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca (2+) -dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca (2+) -independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes (PubMed:23999003) .

Molecular Weight

47573 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Synaptotagmin-1

Subcellular Location

Cytoplasmic vesicle, secretory vesicle membrane

Protein Name

Synaptotagmin-1

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