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Anti-Phospho-EpoR (Y368) Antibody

Boster Bio Anti-Phospho-EpoR (Y368) Antibody catalog # A00427Y368. Tested in ELISA, IF, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Erythropoietin receptor; EPO-R; EPOR;

Gene Name

EPOR

UniProt

P19235

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Epo-R around the phosphorylation site of Tyr368. AA range:341-390

Clonality

Polyclonal

Tissue Specificity

Erythroid cells and erythroid progenitor cells. Isoform EPOR-F is the most abundant form in EPO-dependent erythroleukemia cells and in late-stage erythroid progenitors. Isoform EPOR-S and isoform EPOR-T are the predominant forms in bone marrow. Isoform EPOR-T is the most abundant from in early- stage erythroid progenitor cells.

Applications

WB, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.

Molecular Weight

55065 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Erythropoietin receptor

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Name

Erythropoietin receptor

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