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Anti-Phospho-Dok-1 (Y398) Antibody

Boster Bio Anti-Phospho-Dok-1 (Y398) Antibody catalog # A03039Y398. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Docking protein 1; Downstream of tyrosine kinase 1; p62 (dok) ; pp62; DOK1;

Gene Name

DOK1

UniProt

Q99704

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human p62 Dok around the phosphorylation site of Tyr398. AA range:365-414

Clonality

Polyclonal

Tissue Specificity

Expressed in pancreas, heart, leukocyte and spleen. Expressed in both resting and activated peripheral blood T-cells. Expressed in breast cancer.

Applications

WB, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

Molecular Weight

52392 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Docking protein 1

Subcellular Location

Isoform 1: Cytoplasm. Nucleus.

Protein Name

Docking protein 1

Frequently Asked Questions

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