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Anti-Phospho-NFATc4 (S676) Antibody

Boster Bio Anti-Phospho-NFATc4 (S676) Antibody catalog # A02599S676. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Nuclear factor of activated T-cells, cytoplasmic 4; NF-ATc4; NFATc4; T-cell transcription factor NFAT3; NF-AT3; NFATC4; NFAT3;

Gene Name

NFATC4

UniProt

Q14934

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human NFAT3 around the phosphorylation site of Ser676. AA range:642-691

Clonality

Polyclonal

Tissue Specificity

Highly expressed in placenta, lung, kidney, testis and ovary. Weakly expressed in spleen and thymus. Not expressed in peripheral blood lymphocytes. Detected in hippocampus.

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL- 4. Transcriptionally repressed by estrogen receptors; this inhibition is further enhanced by estrogen. Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation. May play a critical role in cardiac development and hypertrophy. May play a role in deafferentation-induced apoptosis of sensory neurons.

Molecular Weight

95449 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Nuclear factor of activated T-cells, cytoplasmic 4

Subcellular Location

Cytoplasm

Protein Name

Nuclear factor of activated T-cells, cytoplasmic 4

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