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Anti-Phospho-eIF4B (S422) JAK1 Antibody

Boster Bio Anti-Phospho-eIF4B (S422) JAK1 Antibody catalog # A00330S422. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Tyrosine-protein kinase JAK1;2.7.10.2

Gene Name

JAK1

UniProt

P23458

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human eIF4B around the phosphorylation site of Ser422. AA range:388-437

Clonality

Polyclonal

Tissue Specificity

Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue.

Applications

WB, IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway (PubMed:7615558) . Kinase partner for the interleukin (IL) -2 receptor (PubMed:11909529) .

Molecular Weight

133277 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Tyrosine-protein kinase JAK1

Subcellular Location

Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.

Protein Name

Tyrosine-protein kinase JAK1

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