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Anti-Phospho-MEF-2 (T319) MEF2A Antibody

Boster Bio Anti-Phospho-MEF-2 (T319) MEF2A Antibody catalog # A01398T319. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Myocyte-specific enhancer factor 2A; Serum response factor-like protein 1; MEF2A; MEF2;

Gene Name

MEF2A

UniProt

Q02078

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human MEF2A around the phosphorylation site of Thr319. AA range:296-345

Clonality

Polyclonal

Tissue Specificity

Isoform MEF2 and isoform MEFA are expressed only in skeletal and cardiac muscle and in the brain. Isoform RSRFC4 and isoform RSRFC9 are expressed in all tissues examined.

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT] (4) TAR-3', found in numerous muscle- specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.

Molecular Weight

54811 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01398T319

Product MSDS

https://www.bosterbio.com/msds?sku=A01398T319

Fragment

IgG

Other Gene Names

Myocyte-specific enhancer factor 2A

Subcellular Location

Nucleus

Protein Name

Myocyte-specific enhancer factor 2A

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