Anti-Phospho-CD318 (Y707) CDCP1 Antibody

Boster Bio Anti-Phospho-CD318 (Y707) CDCP1 Antibody catalog # A02411Y707. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

CUB domain-containing protein 1; Membrane glycoprotein gp140; Subtractive immunization M plus HEp3-associated 135 kDa protein; SIMA135; Transmembrane and associated with src kinases; CD318; CDCP1; TRASK; UNQ2486/PRO5773;

Gene Name

CDCP1

UniProt

Q9H5V8

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human CD318 (phospho Tyr707)

Clonality

Polyclonal

Tissue Specificity

Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells.

Applications

WB, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.