What is the catalog number for Anti-Phospho-4E-BP1 (T37) EIF4EBP1 Antibody?

The catalog number for Anti-Phospho-4E-BP1 (T37) EIF4EBP1 Antibody is A00968T37-1.

What sizes are available for Anti-Phospho-4E-BP1 (T37) EIF4EBP1 Antibody?

Anti-Phospho-4E-BP1 (T37) EIF4EBP1 Antibody is available in the following size(s): 100 µL.

Is Anti-Phospho-4E-BP1 (T37) EIF4EBP1 Antibody in stock?

Anti-Phospho-4E-BP1 (T37) EIF4EBP1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Phospho-4E-BP1 (T37) EIF4EBP1 Antibody?

The safety data sheet for Anti-Phospho-4E-BP1 (T37) EIF4EBP1 Antibody is available here: https://www.bosterbio.com/msds?sku=A00968T37-1.

Anti-Phospho-4E-BP1 (T37) EIF4EBP1 Antibody

Boster Bio Anti-Phospho-4E-BP1 (T37) EIF4EBP1 Antibody catalog # A00968T37-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Eukaryotic translation initiation factor 4E-binding protein 1;4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I; EIF4EBP1;

Gene Name

EIF4EBP1

UniProt

Q13541

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human 4E-BP1 around the phosphorylation site of Thr36. AA range:4-53

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.