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Anti-Cleaved-Factor XII HC (I20) F12 Antibody

Boster Bio Anti-Cleaved-Factor XII HC (I20) F12 Antibody catalog # A01226-3. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Coagulation factor XII;3.4.21.38; Hageman factor; HAF; Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Coagulation factor XIIa light chain; Beta-factor XIIa part 2; F12;

Gene Name

F12

UniProt

P00748

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human FA12. AA range:1-50

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta- factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.

Molecular Weight

67792 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Coagulation factor XII

Subcellular Location

Secreted.

Protein Name

Coagulation factor XII

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