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Anti-Cleaved-Factor B Bb (K260) CFB Antibody

Boster Bio Anti-Cleaved-Factor B Bb (K260) CFB Antibody catalog # A01260. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Complement factor B;3.4.21.47; C3/C5 convertase; Glycine-rich beta glycoprotein; GBG; PBF2; Properdin factor B; Complement factor B Ba fragment; Complement factor B Bb fragment; CFB; BF, BFD;

Gene Name

CFB

UniProt

P00751

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human CFAB Bb. AA range:241-290

Clonality

Polyclonal

Applications

WB, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B- lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

Molecular Weight

85533 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01260

Product MSDS

https://www.bosterbio.com/msds?sku=A01260

Fragment

IgG

Other Gene Names

Complement factor B

Subcellular Location

Secreted.

Protein Name

Complement factor B

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