Anti-MLKL (phospho S358) Antibody
Boster Bio Anti-MLKL (phospho S358) Antibody catalog # A00535S358. Tested in IHC-P, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Mixed lineage kinase domain-like protein; hMLKL; MLKL
Gene Name
MLKL
UniProt
Q8NB16
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human MLKL (phospho S358)
Clonality
Polyclonal
Applications
IHC-P, WB
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Molecular Weight
54479 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Mixed lineage kinase domain-like protein
Subcellular Location
Cytoplasm
Protein Name
Mixed lineage kinase domain-like protein
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