Anti-Protocadherin Fat 2 FAT2 Antibody
Boster Bio Anti-Protocadherin Fat 2 FAT2 Antibody catalog # A04835. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Protocadherin Fat 2; hFat2; Cadherin family member 8; Multiple epidermal growth factor-like domains protein 1; Multiple EGF-like domains protein 1; FAT2; CDHF8, KIAA0811, MEGF1;
Gene Name
FAT2
UniProt
Q9NYQ8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Tissue Specificity
Expressed in epidermal keratinocytes, infant brain, cerebellum, and also in a variety of tumors, such as pancreatic cancer, diffuse type gastric cancer, ovarian cancer, esophageal cancer, skin squamous cell carcinoma, head and neck cancer. Not expressed in melanoma cell line A375 cells, normal epidermal melanocytes or normal dermal fibroblasts. Expressed in epidermal keratinocytes and squamous cell carcinoma (at protein level) .
Applications
IHC
Purification
FAT2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
IHC-p 1:50-300
Form
Liquid
Function
Involved in the regulation of cell migration (PubMed:18534823) . May be involved in mediating the organization of the parallel fibers of granule cells during cerebellar development (By similarity) .
Molecular Weight
479317 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Protocadherin Fat 2
Subcellular Location
Cell membrane ; Single-pass type I membrane protein . Cell junction
Protein Name
Protocadherin Fat 2
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