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Anti-TIAM1 Antibody

Boster Bio Anti-TIAM1 Antibody catalog # A01745. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

T-lymphoma invasion and metastasis-inducing protein 1; TIAM-1; TIAM1;

Gene Name

TIAM1

UniProt

Q13009

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Found in virtually all analyzed tumor cell lines including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.

Applications

WB, ELISA

Purification

TIAM1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP- dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. Required for normal cell adhesion and cell migration.

Molecular Weight

177508 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

T-lymphoma invasion and metastasis-inducing protein 1

Subcellular Location

Cell junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Detected at the boundary between cells with actin-rich protrusions (By similarity) . Presence of KRIT1, CDH5 and RAP1B is required for its localization to the cell junction. .

Protein Name

T-lymphoma invasion and metastasis-inducing protein 1

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