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Anti-FLVC1 FLVCR1 Antibody

Boster Bio Anti-FLVC1 FLVCR1 Antibody catalog # A05270. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Feline leukemia virus subgroup C receptor-related protein 1; Feline leukemia virus subgroup C receptor; hFLVCR; FLVCR1; FLVCR;

Gene Name

FLVCR1

UniProt

Q9Y5Y0

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from human protein at AA range: 481-530

Clonality

Polyclonal

Tissue Specificity

Found all hematopoietic tissues including peripheral blood lymphocytes. Some expression is found in pancreas and kidney.

Applications

WB, ELISA

Purification

FLVC1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Isoform 1: Heme transporter that exports cytoplasmic heme. It can also export coproporphyrin and protoporphyrin IX, which are both intermediate products in the heme biosynthetic pathway. Does not export bilirubin. Heme export depends on the presence of HPX and is required to maintain intracellular free heme balance, protecting cells from heme toxicity. Heme export provides protection from heme or ferrous iron toxicities in liver, brain, sensory neurons and during erythtopoiesis, a process in which heme synthesis intensifies. Causes susceptibility to FeLV-C in vitro.

Molecular Weight

59863 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Feline leukemia virus subgroup C receptor-related protein 1

Subcellular Location

Isoform 1: Cell membrane ; Multi-pass membrane protein .

Protein Name

Feline leukemia virus subgroup C receptor-related protein 1

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